Search results for " H+-"
showing 10 items of 46 documents
The CD68+/H-ferritin+ cells colonize the lymph nodes of the patients with adult onset Still's disease and are associated with increased extracellular…
2015
Summary In this work, we aimed to evaluate the levels of ferritin enriched in H subunits (H-ferritin) and ferritin enriched in L subunits (L-ferritin) and the cells expressing these two molecules in the lymph node (LN) biopsies obtained from adult-onset Still's disease (AOSD) patients, and the possible correlation among these data and the severity of the disease. Ten patients with AOSD underwent LN biopsy. All the samples were stained by immunofluorescence. A statistical analysis was performed to estimate the possible correlation among both H-ferritin and L-ferritin tissue expression and the clinical picture of the disease. Furthermore, the same analysis was performed to evaluate the possib…
Coordination nano-space as stage of hydrogen ortho–para conversion
2015
The ability to design and control properties of nano-sized space in porous coordination polymers (PCPs) would provide us with an ideal stage for fascinating physical and chemical phenomena. We found an interconversion of nuclear-spin isomers for hydrogen molecule H 2 adsorbed in a Hofmann-type PCP, {Fe(pz)[Pd(CN) 4 ]} (pz=pyrazine), by the temperature dependence of Raman spectra. The ortho (o)–para (p) conversion process of H 2 is forbidden for an isolated molecule. The charge density study using synchrotron radiation X-ray diffraction reveals the electric field generated in coordination nano-space. The present results corroborate similar findings observed on different systems and confirm …
Experimental Evaluation of the Performance of a Three-Phase Five-Level Cascaded H-Bridge Inverter by Means FPGA-Based Control Board for Grid Connecte…
2018
Over the last decades, plants devoted to the generation of green energy significantly increased their number, together with the demand of same electrical energy, also stored in battery systems. This fact produced the growth of energy conversion systems with advanced performances with respect to the traditional ones. In this circumstance, multilevel converters play a significant role for their great advantages in performances, flexibility, fault-tolerability, employment of renewable energy sources and storage systems and finally yet importantly reduced filter requirements. In this context, this paper faces the performance of a cascaded H-bridge 5 level inverter in terms of harmonic distortio…
Oncolytic Virotherapy as Emerging Immunotherapeutic Modality: Potential of Parvovirus H-1
2014
Human tumors develop multiple strategies to evade recognition and efficient suppression by the immune system. Therefore, a variety of immunotherapeutic strategies have been developed to reactivate and reorganize the human immune system. The recent development of new antibodies against immune check points may help to overcome the immune silencing induced by human tumors. Some of these antibodies have already been approved for treatment of various solid tumor entities. Interestingly, targeting antibodies may be combined with standard chemotherapy or radiation protocols. Furthermore, recent evidence indicates that intratumoral (it) or intravenous (iv) injections of replicative oncolytic viruse…
Effective infection, apoptotic cell killing and gene transfer of human hepatoma cells but not primary hepatocytes by parvovirus H1 and derived vector…
2001
Autonomous parvoviruses preferentially replicate in and kill in vitro–transformed cells and reduce the incidence of spontaneous and implanted tumors in animals. Because of these natural oncotropic and oncolytic properties, parvoviruses deserve to be considered as potential antitumor vectors. Here, we assessed whether parvovirus H1 is able to kill human hepatoma cells by induction of apoptosis but spares primary human liver cells, and whether the former cells can efficiently be transduced by H1 virus–based vectors. Cell death, infectivity, and transgene transduction were investigated in Hep3B, HepG2, and Huh7 cells and in primary human hepatocytes with natural and recombinant H1 virus. All h…
Cascaded H-Bridges Multielvel Inverters: grid connected advanced applications
Power electronics is going to increase in the modern electrical systems. It is well known that the use of power electronics allows the management and the control of the energy flow, obtaining voltage and current waveforms suitable for electrical loads. In this scenario, multilevel power converters are finding increased attention in industry and academia as one of the promising choices of electronic conversion thanks to their features and many different application fields with high power and medium voltage. Moreover, they are fundamental in interfacing electric grid to high power renewable energy systems (i.e. PV, Wind farm, Biomass, Fuel Cell etc.). Nowadays, the research is focused on the …
A novel method for harmonic mitigation for single-phase five-level cascaded H-Bridge inverter
2018
The efficiency of a system is a very important parameter for high power electrical drives applications. Moreover, the efficiency of power converters plays a fundamental role. Aim of this work, is to propose a novel selective harmonic mitigation method without solving non-linear equations. Through a very simple approach, the polynomial equations which drive the control angles have been detected for a single-phase five-level cascaded H-Bridge inverter. The obtained polynomial equations can be easily implemented in a digital system to real-time operation. The paper also presents the simulation analysis and experimental validation.
Enhanced Modelling for Extended Performance Analysis of Interior Permanent Magnet Synchronous Machine Drive fed with Cascaded H-Bridges Multilevel In…
2021
This paper presents a comparative simulation analysis of an Interior Permanent Magnet Synchronous Machine (IPMSM) performance once fed by a traditional three-phase two-level inverter and then using a three-phase five-level Cascaded H-Bridges Multilevel Inverter (CHBMI). For this purpose, an enhanced mathematical model of the IPMSM, that take into account simultaneously saturation, cross-coupling, spatial harmonics and iron loss effects, has been employed. Furthermore, two different PWM modulation strategies have been considered. The study was conducted for several working conditions, evaluating the impact of CHBMI adoption on the IPMSM performance in terms of improved efficiency and torque …
What are the effects of the aging of the neuromuscular system on postural stability?
2015
International audience; Aging is frequently associated with a decreased postural stability, essentially after 60 years, leading to an increased risk of falling. In this article we propose to highlight the influence of the aging of the neuromuscular system on postural stability when standing upright. To maintain balance while standing upright, human needs to control the activity of ankle muscles and particularly the plantar flexors. During the aging process, the performance of these muscles are strongly altered. It is commonly observed large deficits in elderly people with history of falls. Some authors reported an inverse correlation between the amplitude of postural sway and the capacity o…
Performance Evaluation of a Three- Phase Five-Level Quasi-Z-Source Cascaded H-Bridge for Grid-Connected Applications
2018
In the field of the PV generation, Quasi-Z-source cascaded H-bridge (qZS-CHB) inverters are promising due to their features of modularity and high voltage conversion ratio. Thus, new topology structures and innovative modulation techniques are continuously being developed to improve the performance in terms of voltage stress and harmonic content. This paper proposes an innovative modulation technique that allows reducing the voltage stress and a specially designed grid-connected control strategy is also introduced. Through simulations in MATLAB, it has been validated that the performance of a three-phase five-level qZS-CHB is improved with the proposed solution.